KDM1B anticorps (Internal Region, N-Term)

N° du produit ABIN6655594

N° du produit (Fournisseur): 100-401-w43

L’anticorps Lapin Polyclonal anti-KDM1B a été validé pour ELISA et WB. Il convient pour détecter KDM1B dans des échantillons de Humain.

Aperçu rapide pour KDM1B anticorps (Internal Region, N-Term) (ABIN6655594)

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM1B est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-KDM1B anticorps

Épitope: Internal Region, N-Term

N° du produit (Fournisseur): 100-401-w43

Fournisseur: Rockland

Fonction: KDM1B Antibody

Réactivité croisée (Details): Cross reactivity with KDM1B from other species not tested.

Purification: Anti-KDM1B Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Stérilité: Sterile filtered

Immunogène: Anti-KDM1B Antibody was produced in rabbits by repeated immunizations with two different synthetic peptides containing a sequence from the N-terminus and internal region of the human KDM1B protein.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1:500

Commentaires:

Anti-KDM1B Antibody has been tested by ELISA. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur KDM1B

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Autre désignation: KDM1B

Sujet:

Synonyms: Lysine-specific histone demethylase 1B, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2, AOF1, C6orf193, LSD2

Background: KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Anti-KDM1B is ideal for research in Epigenetics and Gene Expression.

Gene Name: KDM1B

ID gène: 221656

NCBI Accession: NP_694587

UniProt: Q8NB78

Pathways: L'effet Warburg